It's Times Again
One way to start would be to consider a smaller grid filled with numbers. Perhaps the numbers are all very close together, or perhaps some are much larger than others.
You can use tracing paper to make another version of your grid, and consider some different ways of placing it on top. Without doing all of the calculations, can you see which products are going to be the largest?
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Times
Which times on a digital clock have a line of symmetry? Which look the same upside-down? You might like to try this investigation and find out!
Transformation Tease
What are the coordinates of this shape after it has been transformed in the ways described? Compare these with the original coordinates. What do you notice about the numbers?
Penta Play
A shape and space game for 2, 3 or 4 players. Be the last person to be able to place a pentomino piece on the playing board.